Henry: Cancer Management in Small Animal Practice

Chapter 25: Tumors of the Hematopoietic System


    Section A: Lymphoma

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  8. Pelham JT, Irwin PJ, Kay PH: Genomic hypomethylation in neoplastic cells from dogs with malignant lymphoproliferative disorders, Res Vet Sci 74:101, 2003. Medline abstracts
  9. Fournel-Fleury C, Magnol JP, Bricaire P, et al: Cytohistological and immunological classification of canine malignant lymphomas: comparison with human non-Hodgkin’s lymphomas, J Comp Pathol 117:35, 1997. Medline abstracts
  10. Teske E, Wisman P, Moore PF, et al: Histologic classification and immunophenotyping of canine non-Hodgkin’s lymphomas: unexpected high frequency of T cell lymphomas with B cell morphology, Exp Hematol 22:1179, 1994. Medline abstracts
  11. Maeda H, Ozaki K, Honaga S, et al: Hodgkin’s-like lymphoma in a dog, Zentralbl Veterinarmed A 40:200, 1993. Medline abstracts
  12. Ponce F, Magnol JP, Ledieu D, et al: Prognostic significance of morphological subtypes in canine malignant lymphomas during chemotherapy, Vet J 167:158, 2004. Medline abstracts
  13. Valli VE, Vernau W, de Lorimier LP, et al: Canine indolent nodular lymphoma, Vet Pathol 43:241, 2006. Medline abstracts
  14. Comazzi S, Gelain ME, Riondato F, Paltrinieri S: Flow cytometric expression of common antigens CD18/CD45 in blood from dogs with lymphoid malignancies: a semi-quantitative study, Vet Immunol Immunopathol 112:243, 2006. Medline abstracts
  15. Lana SE, Jackson TL, Burnett RC, et al: Utility of polymerase chain reaction for analysis of antigen receptor rearrangement in staging and predicting prognosis in dogs with lymphoma, J Vet Intern Med 20:329, 2006. Medline abstracts
  16. Tamura K, Yagihara H, Isotani M, et al: Development of the polymerase chain reaction assay based on the canine genome database for detection of monoclonality in B cell lymphoma, Vet Immunol Immunopathol 110:163, 2006. Medline abstracts
  17. Sozmen M, Tasca S, Carli E, et al: Use of fine needle aspirates and flow cytometry for the diagnosis, classification, and immunophenotyping of canine lymphomas, J Vet Diagn Invest 17:323, 2005. Medline abstracts
  18. Wilkerson MJ, Dolce K, Koopman T, et al: Lineage differentiation of canine lymphoma/leukemias and aberrant expression of CD molecules, Vet Immunol Immunopathol 106:179, 2005. Medline abstracts
  19. Gauthier MJ, Aubert I, Abrams-Ogg A, et al: The immunophenotype of peripheral blood lymphocytes in clinically healthy dogs and dogs with lymphoma in remission, J Vet Intern Med 19:193, 2005. Medline abstracts
  20. Gibson D, Aubert I, Woods JP, et al: Flow cytometric immunophenotype of canine lymph node aspirates, J Vet Intern Med 18:710, 2004. Medline abstracts
  21. Keller RL, Avery AC, Burnett RC, et al: Detection of neoplastic lymphocytes in peripheral blood of dogs with lymphoma by polymerase chain reaction for antigen receptor gene rearrangement, Vet Clin Pathol 33:145, 2004. Medline abstracts
  22. Burnett RC, Vernau W, Modiano JF, et al: Diagnosis of canine lymphoid neoplasia using clonal rearrangements of antigen receptor genes, Vet Pathol 40:32, 2003. Medline abstracts
  23. Winnicka A, Jagielski D, Hoffmann-Jagielska M, et al: Cytometric evaluation of peripheral blood lymphocytes in dogs with lymphoma during chemotherapy, J Vet Med A Physiol Pathol Clin Med 49:303, 2002. Medline abstracts
  24. Dreitz MJ, Ogilvie G, Sim GK: Rearranged T lymphocyte antigen receptor genes as markers of malignant T cells, Vet Immunol Immunopathol 69:113, 1999. Medline abstracts
  25. Winkler S, Murua EH, Reimann-Berg N, et al: Cytogenetic investigations in four canine lymphomas, Anticancer Res 25:3995, 2005. Medline abstracts
  26. Bassett CL, Daniel GB, Legendre AM, et al: Characterization of uptake of 2-deoxy-2-[18F] fluoro-D-glucose by fungal-associated inflammation: the standardized uptake value is greater for lesions of blastomycosis than for lymphoma in dogs with naturally occurring disease, Mol Imaging Biol 4:201, 2002. Medline abstracts
  27. MacGregor JM, Faria ML, Moore AS, et al: Cardiac lymphoma and pericardial effusion in dogs: 12 cases (1994-2004), J Am Vet Med Assoc 227:1449, 2005. Medline abstracts
  28. Zoia A, Hughes D, Connolly DJ: Pericardial effusion and cardiac tamponade in a cat with extranodal lymphoma, J Small Anim Pract 45:467, 2004. Medline abstracts
  29. Fry MM, Vernau W, Pesavento PA, et al: Hepatosplenic lymphoma in a dog, Vet Pathol 40:556, 2003. Medline abstracts
  30. French RA, Seitz SE, Valli VE: Primary epitheliotropic alimentary T-cell lymphoma with hepatic involvement in a dog, Vet Pathol 33:349, 1996. Medline abstracts
  31. Aquino SM, Hamor RE, Valli VE, et al: Progression of an orbital T-cell rich B-cell lymphoma to a B-cell lymphoma in a dog, Vet Pathol 37:465, 2000. Medline abstracts
  32. Vascellari M, Multari D, Mutinelli F: Unicentric extranodal lymphoma of the upper eyelid conjunctiva in a dog, Vet Ophthalmol 8:67, 2005. Medline abstracts
  33. Donaldson D, Day MJ: Epitheliotropic lymphoma (mycosis fungoides) presenting as blepharoconjunctivitis in an Irish setter, J Small Anim Pract 41:317, 2000. Medline abstracts
  34. Radi ZA, Miller DL, Hines ME: B-cell conjunctival lymphoma in a cat, Vet Ophthalmol 7:413, 2004. Medline abstracts
  35. Lahmers SM, Mealey KL, Martinez SA, et al: Synovial T-cell lymphoma of the stifle in a dog, J Am Anim Hosp Assoc 38:165, 2002. Medline abstracts
  36. Ueno H, Isomura H, Tanabe S, et al: Solitary nonepitheliotropic T-cell lymphoma in a dog, J Vet Med Sci 66:437, 2004. Medline abstracts
  37. de Lorimier LP: Updates on the management of canine epitheliotropic cutaneous T-cell lymphoma, Vet Clin North Am Small Anim Pract 36:213, 2006. Medline abstracts
  38. Bouchard H: Epitheliotropic lymphoma in a dog, Can Vet J 41:628, 2000. Medline abstracts
  39. Tobey JC, Houston DM, Breur GJ, et al: Cutaneous T-cell lymphoma in a cat, J Am Vet Med Assoc 204:606, 1994. Medline abstracts
  40. Schick RO, Murphy GF, Goldschmidt MH: Cutaneous lymphosarcoma and leukemia in a cat, J Am Vet Med Assoc 203:1155, 1993. Medline abstracts
  41. Komori S, Nakamura S, Takahashi K, et al: Use of lomustine to treat cutaneous nonepitheliotropic lymphoma in a cat, J Am Vet Med Assoc 226:237, 2005. Medline abstracts
  42. Miura T, Maruyama H, Sakai M, et al: Endoscopic findings on alimentary lymphoma in 7 dogs, J Vet Med Sci 66:577, 2004. Medline abstracts
  43. Ozaki K, Yamagami T, Nomura K, et al: T-cell lymphoma with eosinophilic infiltration involving the intestinal tract in 11 dogs, Vet Pathol 43:339, 2006. Medline abstracts
  44. Milner RJ, Peyton J, Cooke K, et al: Response rates and survival times for cats with lymphoma treated with the University of Wisconsin-Madison chemotherapy protocol: 38 cases (1996-2003), J Am Vet Med Assoc 227:1118, 2005. Medline abstracts
  45. Waly NE, Gruffydd-Jones TJ, Stokes CR, et al: Immunohistochemical diagnosis of alimentary lymphomas and severe intestinal inflammation in cats, J Comp Pathol 133:253, 2005. Medline abstracts
  46. Louwerens M, London CA, Pedersen NC, et al: Feline lymphoma in the post-feline leukemia virus era, J Vet Intern Med 19:329, 2005. Medline abstracts
  47. Barrs VR, Beatty JA, McCandlish IA, et al: Hypereosinophilic paraneoplastic syndrome in a cat with intestinal T cell lymphosarcoma, J Small Anim Pract 43:401, 2002. Medline abstracts
  48. Carreras JK, Goldschmidt M, Lamb M, et al: Feline epitheliotropic intestinal malignant lymphoma: 10 cases (1997-2000), J Vet Intern Med 17:326, 2003. Medline abstracts
  49. Jackson ML, Wood SL, Misra V, et al: Immunohistochemical identification of B and T lymphocytes in formalin-fixed, paraffin-embedded feline lymphosarcomas: relation to feline leukemia virus status, tumor site, and patient age, Can J Vet Res 60:199, 1996. Medline abstracts
  50. Mahony OM, Moore AS, Cotter SM, et al: Alimentary lymphoma in cats: 28 cases (1988-1993), J Am Vet Med Assoc 207:1593, 1995. Medline abstracts
  51. Richter KP: Feline gastrointestinal lymphoma, Vet Clin North Am Small Anim Pract 33:1083, vii, 2003. Medline abstracts
  52. Patterson-Kane JC, Kugler BP, Francis K: The possible prognostic significance of immunophenotype in feline alimentary lymphoma: a pilot study, J Comp Pathol 130:220, 2004. Medline abstracts
  53. Fournel-Fleury C, Ponce F, Felman P, et al: Canine T-cell lymphomas: a morphological, immunological, and clinical study of 46 new cases, Vet Pathol 39:92, 2002. Medline abstracts
  54. Bolliger AP, Graham PA, Richard V, et al: Detection of parathyroid hormone-related protein in cats with humoral hypercalcemia of malignancy, Vet Clin Pathol 31:3, 2002. Medline abstracts
  55. Savary KC, Price GS, Vaden SL: Hypercalcemia in cats: a retrospective study of 71 cases (1991-1997), J Vet Intern Med 14:184, 2000. Medline abstracts
  56. Bennett SL, Slocombe RF, Holloway SA, et al: Lymphoma(s) showing epitheliotropism and diffuse skeletal muscle involvement presenting as a polymyopathy in a young dog, Aust Vet J 83:612, 2005. Medline abstracts
  57. Harkin KR, Kennedy GA, Moore WE, et al: Skeletal muscle lymphoma in a bullmastiff, J Am Anim Hosp Assoc 36:63, 2000. Medline abstracts
  58. Krecic MR, Black SS: Epitheliotropic T-cell gastrointestinal tract lymphosarcoma with metastases to lung and skeletal muscle in a cat, J Am Vet Med Assoc 216:524, 517, 2000. Medline abstracts
  59. Dhaliwal RS, Reed AL, Kitchell BE: Multicentric lymphosarcoma in a dog with multiple-site skeletal involvement, Vet Radiol Ultrasound 42:38, 2001. Medline abstracts
  60. Mellanby RJ, Jeffery ND, Baines EA, et al: Magnetic resonance imaging in the diagnosis of lymphoma involving the brachial plexus in a cat, Vet Radiol Ultrasound 44:522, 2003. Medline abstracts
  61. Lane SB, Kornegay JN, Duncan JR, et al: Feline spinal lymphosarcoma: a retrospective evaluation of 23 cats, J Vet Intern Med 8:99, 1994. Medline abstracts
  62. Spodnick GJ, Berg J, Moore FM, et al: Spinal lymphoma in cats: 21 cases (1976-1989), J Am Vet Med Assoc 200:373, 1992. Medline abstracts
  63. Tomek A, Cizinauskas S, Doherr M, et al: Intracranial neoplasia in 61 cats: localisation, tumour types and seizure patterns, J Feline Med Surg 8:243, 2006. Medline abstracts
  64. de Lorimier LP, Alexander SD, Fan TM: T-cell lymphoma of the tympanic bulla in a feline leukemia virus-negative cat, Can Vet J 44:987, 2003. Medline abstracts
  65. Ridge L, Swinney G: Angiotrophic intravascular lymphosarcoma presenting as bi-cavity effusion in a dog, Aust Vet J 82:616, 2004. Medline abstracts
  66. Bush WW, Throop JL, McManus PM, et al: Intravascular lymphoma involving the central and peripheral nervous systems in a dog, J Am Anim Hosp Assoc 39:90, 2003. Medline abstracts
  67. McDonough SP, Van Winkle TJ, Valentine BA, et al: Clinicopathological and immunophenotypical features of canine intravascular lymphoma (malignant angioendotheliomatosis), J Comp Pathol 126:277, 2002. Medline abstracts
  68. Cullen CL, Caswell JL, Grahn BH: Intravascular lymphoma presenting as bilateral panophthalmitis and retinal detachment in a dog, J Am Anim Hosp Assoc 36:337, 2000. Medline abstracts
  69. Lapointe JM, Higgins RJ, Kortz GD, et al: Intravascular malignant T-cell lymphoma (malignant angioendotheliomatosis) in a cat, Vet Pathol 34:247, 1997. Medline abstracts
  70. Shankel CA: Choanal lymphosarcoma in a 7-year-old golden retriever: diagnosis and treatment, Can Vet J 46:166, 2005. Medline abstracts
  71. Kaldrymidou E, Papaioannou N, Poutahidis T, et al: Malignant lymphoma in nasal cavity and paranasal sinuses of a dog, J Vet Med A Physiol Pathol Clin Med 47:457, 2000. Medline abstracts
  72. Straw RC, Withrow SJ, Gillette EL, et al: Use of radiotherapy for the treatment of intranasal tumors in cats: six cases (1980-1985), J Am Vet Med Assoc 189:927, 1986. Medline abstracts
  73. Henderson SM, Bradley K, Day MJ, et al: Investigation of nasal disease in the cat—a retrospective study of 77 cases, J Feline Med Surg 6:245, 2004. Medline abstracts
  74. Mukaratirwa S, van der Linde-Sipman JS, Gruys E: Feline nasal and paranasal sinus tumours: clinicopathological study, histomorphological description and diagnostic immunohistochemistry of 123 cases, J Feline Med Surg 3:235, 2001. Medline abstracts
  75. Kim DY, Kim JR, Taylor HW, et al: Primary extranodal lymphosarcoma of the trachea in a cat, J Vet Med Sci 58:703, 1996. Medline abstracts
  76. Batchelor DJ, Bright SR, Ibarrola P, et al: Long-term survival after combination chemotherapy for bilateral renal malignant lymphoma in a dog, N Z Vet J 54:147, 2006. Medline abstracts
  77. Mooney SC, Hayes AA, Matus RE, et al: Renal lymphoma in cats: 28 cases (1977-1984), J Am Vet Med Assoc 191:1473, 1987. Medline abstracts
  78. Maiolino P, DeVico G: Primary epitheliotropic T-cell lymphoma of the urinary bladder in a dog, Vet Pathol 37:184, 2000. Medline abstracts
  79. Struble AL, Lawson GW, Ling GV: Urethral obstruction in a dog: an unusual presentation of T-cell lymphoma, J Am Anim Hosp Assoc 33:423, 1997. Medline abstracts
  80. Ridyard AE, Rhind SM, French AT, et al: Myasthenia gravis associated with cutaneous lymphoma in a dog, J Small Anim Pract 41:348, 2000. Medline abstracts
  81. Marchetti V, Benetti C, Citi S, et al: Paraneoplastic hypereosinophilia in a dog with intestinal T-cell lymphoma, Vet Clin Pathol 34:259, 2005. Medline abstracts
  82. Coyle KA, Steinberg H: Characterization of lymphocytes in canine gastrointestinal lymphoma, Vet Pathol 41:141, 2004. Medline abstracts
  83. Garrett LD, Thamm DH, Chun R, et al: Evaluation of a 6-month chemotherapy protocol with no maintenance therapy for dogs with lymphoma, J Vet Intern Med 16:704, 2002. Medline abstracts
  84. Moore AS, Cotter SM, Rand WM, et al: Evaluation of a discontinuous treatment protocol (VELCAP-S) for canine lymphoma, J Vet Intern Med 15:348, 2001. Medline abstracts
  85. MacDonald VS, Thamm DH, Kurzman ID, et al: Does L-asparaginase influence efficacy or toxicity when added to a standard CHOP protocol for dogs with lymphoma? J Vet Intern Med 19:732, 2005. Medline abstracts
  86. Jeffreys AB, Knapp DW, Carlton WW, et al: Influence of asparaginase on a combination chemotherapy protocol for canine multicentric lymphoma, J Am Anim Hosp Assoc 41:221, 2005. Medline abstracts
  87. Valerius KD, Ogilvie GK, Fettman MJ, et al: Comparison of the effects of asparaginase administered subcutaneously versus intramuscularly for treatment of multicentric lymphoma in dogs receiving doxorubicin, J Am Vet Med Assoc 214:353, 1999. Medline abstracts
  88. Bergman PJ, Ogilvie GK, Powers BE: Monoclonal antibody C219 immunohistochemistry against P-glycoprotein: sequential analysis and predictive ability in dogs with lymphoma, J Vet Intern Med 10:354, 1996. Medline abstracts
  89. Lee JJ, Hughes CS, Fine RL, et al: P-glycoprotein expression in canine lymphoma: a relevant, intermediate model of multidrug resistance, Cancer 77:1892, 1996. Medline abstracts
  90. Moore AS, Leveille CR, Reimann KA, et al: The expression of P-glycoprotein in canine lymphoma and its association with multidrug resistance, Cancer Invest 13:475, 1995. Medline abstracts
  91. Culmsee K, Gruber AD, von Samson-Himmelstjerna G, et al: Quantification of MDR-1 gene expression in canine tissues by real-time reverse transcription quantitative polymerase chain reaction, Res Vet Sci 77:223, 2004. Medline abstracts
  92. Sueiro FA, Alessi AC, Vassallo J: Canine lymphomas: a morphological and immunohistochemical study of 55 cases, with observations on p53 immunoexpression, J Comp Pathol 131:207, 2004. Medline abstracts
  93. Mealey KL, Northrup NC, Bentjen SA: Increased toxicity of P-glycoprotein-substrate chemotherapeutic agents in a dog with the MDR1 deletion mutation associated with ivermectin sensitivity, J Am Vet Med Assoc 223:1453, 1434, 2003. Medline abstracts
  94. Khanna C, Lund EM, Redic KA, et al: Randomized controlled trial of doxorubicin versus dactinomycin in a multiagent protocol for treatment of dogs with malignant lymphoma, J Am Vet Med Assoc 213:985, 1998. Medline abstracts
  95. Moore AS, Ogilvie GK, Ruslander D, et al: Evaluation of mitoxantrone for the treatment of lymphoma in dogs, J Am Vet Med Assoc 204:1903, 1994. Medline abstracts
  96. Lucroy MD, Phillips BS, Kraegel SA, et al: Evaluation of single-agent mitoxantrone as chemotherapy for relapsing canine lymphoma, J Vet Intern Med 12:325, 1998. Medline abstracts
  97. Williams LE, Rassnick KM, Power HT, et al: CCNU in the treatment of canine epitheliotropic lymphoma, J Vet Intern Med 20:136, 2006. Medline abstracts
  98. Bhang DH, Choi US, Kim MK, et al: Epitheliotropic cutaneous lymphoma (mycosis fungoides) in a dog, J Vet Sci 7:97, 2006. Medline abstracts
  99. Frimberger AE, Moore AS, Rassnick KM, et al: A combination chemotherapy protocol with dose intensification and autologous bone marrow transplant (VELCAP-HDC) for canine lymphoma, J Vet Intern Med 20:355, 2006. Medline abstracts
  100. Lupu M, Sullivan EW, Westfall TE, et al: Use of multigeneration-family molecular dog leukocyte antigen typing to select a hematopoietic cell transplant donor for a dog with T-cell lymphoma, J Am Vet Med Assoc 228:728, 2006. Medline abstracts
  101. Williams LE, Johnson JL, Hauck ML, et al: Chemotherapy followed by half-body radiation therapy for canine lymphoma, J Vet Intern Med 18:703, 2004. Medline abstracts
  102. Brown EM, Ruslander DM, Azuma C, et al: A feasibility study of low-dose total body irradiation for relapsed canine lymphoma, Vet Comp Oncol 4:75, 2006. Medline abstracts
  103. Prescott D.M., Gordon J: Total skin electron beam irradiation for generalized cutaneous lymphoma, Vet Comp Oncol 3:32, 2005.
  104. Ogilvie GK, Fettman MJ, Mallinckrodt CH, et al: Effect of fish oil, arginine, and doxorubicin chemotherapy on remission and survival time for dogs with lymphoma: a double-blind, randomized placebo-controlled study, Cancer 88:1916, 2000. Medline abstracts
  105. Selting KA, Ogilvie GK, Gustafson DL, et al: Evaluation of the effects of dietary n-3 fatty acid supplementation on the pharmacokinetics of doxorubicin in dogs with lymphoma, Am J Vet Res 67:145, 2006. Medline abstracts
  106. McNiel EA, Ogilvie GK, Mallinckrodt C, et al: Platelet function in dogs treated for lymphoma and hemangiosarcoma and supplemented with dietary n-3 fatty acids, J Vet Intern Med 13:574, 1999. Medline abstracts
  107. Carter RF, Harris CK, Withrow SJ: Chemotherapy of canine lymphoma with histopathological correlation: doxorubicin alone compared to COP as first treatment regimen, J Am Anim Hosp Assoc 23:221, 1987.
  108. Cotter SM, Goldstein MA: Treatment of lymphoma and leukemia with cyclophosphamide, vincristine, and prednisone, J Am Anim Hosp Assoc 19:159, 1983.
  109. Gustafson NR, Lana SE, Mayer MN, et al: A preliminary assessment of whole-body radiotherapy interposed within a chemotherapy protocol for canine lymphoma, Vet Comp Oncol 2:125, 2004. Medline abstracts
  110. Hammer AS, Couto CG, Ayl RD, et al: Treatment of tumor-bearing dogs with actinomycin D, J Vet Intern Med 8:236, 1994. Medline abstracts
  111. Moore AS, Ogilvie GK, Vail DM: Actinomycin D for reinduction of remission in dogs with resistant lymphoma, J Vet Intern Med 8:343, 1994. Medline abstracts
  112. Calvert CA, Leifer CE: Doxorubicin for treatment of canine lymphosarcoma after development of resistance to combination chemotherapy, J Am Vet Med Assoc 179:1011, 1981. Medline abstracts
  113. Van Vechten M, Helfand SC, Jeglum KA: Treatment of relapsed canine lymphoma with doxorubicin and dacarbazine, J Vet Intern Med 4:187, 1990. Medline abstracts
  114. Rassnick KM, Mauldin GE, Al-Sarraf R, et al: MOPP chemotherapy for treatment of resistant lymphoma in dogs: a retrospective study of 117 cases (1989-2000), J Vet Intern Med 16:576, 2002. Medline abstracts
  115. Hohenhaus AE, Matus RE: Etoposide (VP-16). Retrospective analysis of treatment in 13 dogs with lymphoma, J Vet Intern Med 4:239, 1990. Medline abstracts
  116. Moore AS, London CA, Wood CA, et al: Lomustine (CCNU) for the treatment of resistant lymphoma in dogs, J Vet Intern Med 13:395, 1999. Medline abstracts
  117. LeBlanc AK, Mauldin GE, Milner RJ, et al: Efficacy and toxicity of BOPP and LOPP chemotherapy for the treatment of relapsed canine lymphoma, Vet Comp Oncol 4:21, 2006. Medline abstracts
  118. Henry CJ, McCaw DL, Brock KV, et al: Association between cancer chemotherapy and canine distemper virus, canine parvovirus, and rabies virus antibody titers in tumor-bearing dogs, J Am Vet Med Assoc 219:1238, 2001. Medline abstracts
  119. Walter CU, Biller BJ, Lana SE, et al: Effects of chemotherapy on immune responses in dogs with cancer, J Vet Intern Med 20:342, 2006. Medline abstracts
  120. Shelton GH, Grant CK, Cotter SM, et al: Feline immunodeficiency virus and feline leukemia virus infections and their relationships to lymphoid malignancies in cats: a retrospective study (1968-1988), J Acquir Immune Defic Syndr 3:623, 1990. Medline abstracts
  121. Reinacher M: Diseases associated with spontaneous feline leukemia virus (FeLV) infection in cats, Vet Immunol Immunopathol 21:85, 1989. Medline abstracts
  122. Bertone ER, Snyder LA, Moore AS: Environmental tobacco smoke and risk of malignant lymphoma in pet cats, Am J Epidemiol 156:268, 2002. Medline abstracts
  123. Wooldridge JD, Gregory CR, Mathews KG, et al: The prevalence of malignant neoplasia in feline renal-transplant recipients, Vet Surg 31:94, 2002. Medline abstracts
  124. Gregory CR, Madewell BR, Griffey SM, et al: Feline leukemia virus-associated lymphosarcoma following renal transplantation in a cat, Transplantation 52:1097, 1991. Medline abstracts
  125. Madewell BR, Gieger TL, Pesavento PA, et al: Vaccine site-associated sarcoma and malignant lymphoma in cats: a report of six cases (1997-2002), J Am Anim Hosp Assoc 40:47, 2004. Medline abstracts
  126. Gabor LJ, Malik R, Canfield PJ: Clinical and anatomical features of lymphosarcoma in 118 cats, Aust Vet J 76:725, 1998. Medline abstracts
  127. Parnell NK, Powell LL, Hohenhaus AE, et al: Hypoadrenocorticism as the primary manifestation of lymphoma in two cats, J Am Vet Med Assoc 214:1208, 1200, 1999. Medline abstracts
  128. Court EA, Watson AD, Peaston AE: Retrospective study of 60 cases of feline lymphosarcoma, Aust Vet J 75:424, 1997. Medline abstracts
  129. Gabor LJ, Love DN, Malik R, et al: Feline immunodeficiency virus status of Australian cats with lymphosarcoma, Aust Vet J 79:540, 2001. Medline abstracts
  130. Gabor LJ, Jackson ML, Trask B, et al: Feline leukaemia virus status of Australian cats with lymphosarcoma, Aust Vet J 79:476, 2001. Medline abstracts
  131. Gabor LJ, Canfield PJ, Malik R: Haematological and biochemical findings in cats in Australia with lymphosarcoma, Aust Vet J 78:456, 2000. Medline abstracts
  132. Malik R, Gabor LJ, Foster SF, et al: Therapy for Australian cats with lymphosarcoma, Aust Vet J 79:808, 2001. Medline abstracts
  133. Teske E, van Straten G, van Noort R, Rutteman GR: Chemotherapy with cyclophosphamide, vincristine, and prednisolone (COP) in cats with malignant lymphoma: new results with an old protocol, J Vet Intern Med 16:179, 2002. Medline abstracts
  134. Tromblee TC, Jones JC, Etue AE, et al: Association between clinical characteristics, computed tomography characteristics, and histologic diagnosis for cats with sinonasal disease, Vet Radiol Ultrasound 47:241, 2006. Medline abstracts
  135. Werner JA, Woo JC, Vernau W, et al: Characterization of feline immunoglobulin heavy chain variable region genes for the molecular diagnosis of B-cell neoplasia, Vet Pathol 42:596, 2005. Medline abstracts
  136. Moore PF, Woo JC, Vernau W, et al: Characterization of feline T cell receptor gamma (TCRG) variable region genes for the molecular diagnosis of feline intestinal T cell lymphoma, Vet Immunol Immunopathol 106:167, 2005. Medline abstracts
  137. Walton RM, Hendrick MJ: Feline Hodgkin’s-like lymphoma: 20 cases (1992-1999), Vet Pathol 38:504, 2001. Medline abstracts
  138. Holt E, Goldschmidt MH, Skorupski K: Extranodal conjunctival Hodgkin’s-like lymphoma in a cat, Vet Ophthalmol 9:141, 2006. Medline abstracts
  139. Hutson CA, Rideout BA, Pedersen NC: Neoplasia associated with feline immunodeficiency virus infection in cats of southern California, J Am Vet Med Assoc 199:1357, 1991. Medline abstracts
  140. Day MJ, Henderson SM, Belshaw Z, et al: An immunohistochemical investigation of 18 cases of feline nasal lymphoma, J Comp Pathol 130:152, 2004. Medline abstracts
  141. de Lorimier LP, Fan TM, Haney S, et al: Feline sinonasal neoplasia: CT staging and prognosis with mega voltage radiation therapy, Vet Comp Oncol 3:39, 2005.
  142. Evans SM, Hendrick M: Radiotherapy of feline nasal tumors, Vet Radiol Ultrasound 30:128, 1989.
  143. Roccabianca P, Vernau W, Caniatti M, et al: Feline large granular lymphocyte (LGL) lymphoma with secondary leukemia: primary intestinal origin with predominance of a CD3/CD8(alpha)(alpha) phenotype, Vet Pathol 43:15, 2006. Medline abstracts
  144. Moore AS, Cotter SM, Frimberger AE, et al: A comparison of doxorubicin and COP for maintenance of remission in cats with lymphoma, J Vet Intern Med 10:372, 1996. Medline abstracts
  145. Ettinger SN: Principles of treatment for feline lymphoma, Clin Tech Small Anim Pract 18:98, 2003. Medline abstracts
  146. Vail DM, Moore AS, Ogilvie GK, et al: Feline lymphoma (145 cases): proliferation indices, cluster of differentiation 3 immunoreactivity, and their association with prognosis in 90 cats, J Vet Intern Med 12:349, 1998. Medline abstracts
  147. Kristal O, Lana SE, Ogilvie GK, et al: Single agent chemotherapy with doxorubicin for feline lymphoma: a retrospective study of 19 cases (1994-1997), J Vet Intern Med 15:125, 2001. Medline abstracts
  148. Peaston AE, Maddison JE: Efficacy of doxorubicin as an induction agent for cats with lymphosarcoma, Aust Vet J 77:442, 1999. Medline abstracts
  149. Rassnick KM, Gieger TL, Williams LE, et al: Phase I evaluation of CCNU (lomustine) in tumor-bearing cats, J Vet Intern Med 15:196, 2001. Medline abstracts
  150. Elmslie RE, Ogilvie GK, Gillette EL, et al: Radiotherapy with and without chemotherapy for localized lymphoma in cats, Vet Radiol Ultrasound 32:277, 1991.
  151. Zwahlen CH, Lucroy MD, Kraegel SA, et al: Results of chemotherapy for cats with alimentary malignant lymphoma: 21 cases (1993-1997), J Am Vet Med Assoc 213:1144, 1998. Medline abstracts
  152. Fondacaro JV, Richter KP, Carpenter JL, et al: Feline gastrointestinal lymphoma: 67 cases (1988-1996), Eur J Comp Gastroenterol 4:5, 1999.

Section B: Leukemia

  1. Priester WA, McKay FW: The occurrence of tumors in domestic animals, J Natl Cancer Inst 54:1, 1980. Medline abstracts
  2. Hardy WD: Hematopoietic tumors of cats, J Am Anim Hosp Assoc 17:921, 1981.
  3. Smith M, Turrel JM: Radiophosphorus (32P) treatment of bone marrow disorders in dogs: 11 cases (1970-1987), J Am Vet Med Assoc 194:98, 1989. Medline abstracts
  4. Hisasue M, Okayama H, Okayama T: Hematologic abnormalities and outcome of 16 cats with myelodysplastic syndromes, J Vet Intern Med 15:471, 2001. Medline abstracts
  5. Ghernati I, Corbin A, Chabanne L, et al: Canine large granular lymphocyte leukemia and its derived cell line produce infectious retroviral particles, Vet Pathol 37:310, 2000. Medline abstracts
  6. Shifrine M, Bulgin MS, Dollarhide NE: Transplantation of radiation-induced canine myelomonocytic leukaemia, Nature 232:405, 1971. Medline abstracts
  7. Kawakami T, Cain G, Taylor N: Establishment and partial characterization of a radiation-induced canine monocytic leukemic cell line, Leuk Res 13:709, 1989. Medline abstracts
  8. Steel RJ: Lymphoid leucaemia in a dog after chemotherapy for mast cell sarcomas, Aust Vet J 66:108, 1989. Medline abstracts
  9. Vernau W, Moore PF: An immunophenotypic study of canine leukemias and preliminary assessment of clonality by polymerase chain reaction, Vet Immunol Immunopathol 69:145, 1999. Medline abstracts
  10. Matus RE, Leifer CE, MacEwen EG: Acute lymphoblastic leukemia in the dog: a review of 30 cases, J Am Vet Med Assoc 183:859, 1983. Medline abstracts
  11. Leifer CE, Matus RE: Chronic lymphocytic leukemia in the dog: 22 cases (1974-1984), J Am Vet Med Assoc 189:214, 1986. Medline abstracts
  12. Leifer CE, Matus RE, Patnaik AK, et al: Chronic myelogenous leukemia in the dog, J Am Vet Med Assoc 183:686, 1983. Medline abstracts
  13. Blue JT, French TW, Kranz JS: Non-lymphoid hematopoietic neoplasia in cats: a retrospective study of 60 cases, Cornel Vet 78:21, 1988.
  14. Jain NC, Blue JT, Grindem CB, et al: Proposed criteria for classification of acute myeloid leukemia in dogs and cats, Vet Clin Pathol 20:63, 1991. Medline abstracts
  15. Young KM, MacEwen EG: Canine myeloproliferative disorders. In Withrow SJ, MacEwen EG (eds): Small animal clinical oncology. Philadelphia, 2001, WB Saunders.
  16. Lupu M, Sullivan EW, Westfall TE: Use of multigeneration-family molecular dog leukocyte antigen typing to select a hematopoietic cell transplant donor for a dog with T-cell lymphoma, J Am Vet Med Assoc 228:28, 2006. Medline abstracts
  17. MacEwen EG, Patnaik AK, Hayes AA, et al: Temporary plasma-induced remission of lymphoblastic leukemia in a dog, Am J Vet Res 42:1450, 1981. Medline abstracts
  18. Harvey JW, Terrell TG, Hyde DM, Jackson RI: Well-differentiated lymphocytic leukemia in a dog: long-term survival without therapy, Vet Pathol 18:37, 1981. Medline abstracts
  19. Meyer HP, Slappendel RJ, Greydanus-van der Putten SW: Polycythemia vera in a dog treated by repeated phlebotomies, Vet Q 15:108, 1993. Medline abstracts

Section C: Multiple Myeloma

  1. Ramaiah SK, Seguin MA, Carwile HF, Raskin RE: Biclonal gammopathy associated with immunoglobulin A in a dog with multiple myeloma, Vet Clin Pathol 31:83, 2002. Medline abstracts
  2. Peterson EN, Meininger AC: Immunoglobulin A and immunoglobulin G biclonal gammopathy in a dog with multiple myeloma, J Am Anim Hosp Assoc 33:45, 1997. Medline abstracts
  3. Stockham SL, Scott MA: Proteins. In Stockham SL, Scott MA (eds): Fundamentals of veterinary clinical pathology, ed 1. Ames, IA, 2002, Iowa State Press, p 251.
  4. Tripp CD, Bryan JN, Wills TB: Presumptive increase in protein-bound serum calcium in a dog with multiple myeloma, Vet Clin Pathol 38:87, 2009. Medline abstracts
  5. Matus RE, Leifer CE, MacEwen EG, et al: Prognostic factors for multiple myeloma in the dog, J Am Vet Med Assoc 188:1288, 1986. Medline abstracts
  6. Imahori S, Moore GE: Multiple myeloma and prolonged stimulation of reticuloendothelial system, N Y State J Med 72:1625, 1972. Medline abstracts
  7. Hanna F: Multiple myelomas in cats, J Feline Med Surg 7:275, 2005. Medline abstracts
  8. Radhakrishnan A, Risbon RE, Patel RT, et al: Progression of a solitary, malignant cutaneous plasma-cell tumour to multiple myeloma in a cat, Vet Comp Oncol 2:36, 2004. Medline abstracts
  9. Bienzle D, Silverstein DC, Chaffin K: Multiple myeloma in cats: variable presentation with different immunoglobulin isotypes in two cats, Vet Pathol 37:364, 2000. Medline abstracts
  10. Osborne CA, Perman V, Sautter JH, et al: Multiple myeloma in the dog, J Am Vet Med Assoc 153:1300, 1968. Medline abstracts
  11. Patel RT, Caceres A, French AF, et al: Multiple myeloma in 16 cats: a retrospective study, Vet Clin Pathol 34:341, 2005. Medline abstracts
  12. Sheafor SE, Gamblin RM, Couto CG: Hypercalcemia in two cats with multiple myeloma, J Am Anim Hosp Assoc 32:503, 1996. Medline abstracts
  13. Drazner FH: Hypercalcemia in the dog and cat, J Am Vet Med Assoc 178:1252, 1981. Medline abstracts
  14. MacEwen EG, Hurvitz AI: Diagnosis and management of monoclonal gammopathies, Vet Clin North Am 7:119, 1977. Medline abstracts
  15. Dispenzieri A, Kyle R, Merlini G, et al: International Myeloma Working Group guidelines for serum-free light chain analysis in multiple myeloma and related disorders, Leukemia 23:215, 2009. Medline abstracts
  16. Kyle RA, Rajkumar SV: Criteria for diagnosis, staging, risk stratification and response assessment of multiple myeloma, Leukemia 23:3, 2009. Medline abstracts
  17. Alexiou C, Kau RJ, Dietzfelbinger H, et al: Extramedullary plasmacytoma: tumor occurrence and therapeutic concepts, Cancer 85:2305, 1999. Medline abstracts
  18. Wright ZM, Rogers KS, Mansell J: Survival data for canine oral extramedullary plasmacytomas: a retrospective analysis (1996-2006), J Am Anim Hosp Assoc 44:75, 2008. Medline abstracts
  19. Clark GN, Berg J, Engler SJ, et al: Extramedullary plasmacytomas in dogs: 75 cases, J Am Anim Hosp Assoc 28:105, 1992.
  20. Cangul IT, Wijnen M, Van GE, et al: Clinico-pathological aspects of canine cutaneous and mucocutaneous plasmacytomas, J Vet Med A Physiol Pathol Clin Med 49:307, 2002. Medline abstracts
  21. Baer KE, Patnaik AK, Gilbertson SR, et al: Cutaneous plasmacytomas in dogs: a morphologic and immunohistochemical study, Vet Pathol 26:216, 1989. Medline abstracts
  22. Mellor PJ, Haugland S, Murphy S, et al: Myeloma-related disorders in cats commonly present as extramedullary neoplasms in contrast to myeloma in human patients: 24 cases with clinical follow-up, J Vet Intern Med 20:1376, 2006. Medline abstracts
  23. Kitchell BE, Dhaliwal RS: CVT update: anticancer drugs and protocols using traditional drugs. In Bonagura JD (ed): Kirk’s current veterinary therapy, ed 13. Philadelphia, 2000, WB Saunders, p 465.
  24. Rusbridge C, Wheeler SJ, Lamb CR, et al: Vertebral plasma cell tumors in 8 dogs, J Vet Intern Med 13:126, 1999. Medline abstracts